| 甘氨酸螯合铁纳米脂质体对缺铁性贫血大鼠的补铁效果
| Effectiveness of Treatment of Iron-Deficiency Anemia in Rats with Ferrous Glycinate Nanoliposomes
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| DOI：10.3969/j.issn.1673-1689.2011.01.009
| 中文关键词: 甘氨酸螯合铁纳米脂质体 缺铁性贫血 大鼠 补铁
| 英文关键词: ferrous glycinate nanoliposome iron-deficiency anemia rat iron repletion
| 基金项目:国家863计划项目(2007AA100403);江苏省科技支撑计划项目(BE2008326)
| 作者
| 单位
| 丁保淼
| 江南大学食品学院,江苏,无锡,214122
| 张晓鸣
| 食品科学与技术国家重点实验室,江南大学,江苏,无锡,214122
江南大学食品学院,江苏,无锡,214122
| 夏书芹
| 江南大学食品学院,江苏,无锡,214122
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| 中文摘要:
| 研究了甘氨酸螯合铁纳米脂质体作为补铁剂对缺铁性贫血大鼠的补铁效果。通过对SD品系初断乳大鼠喂养缺铁基础饲料,建立缺铁性贫血大鼠模型,再用甘氨酸螯合铁纳米脂质体对缺铁性贫血大鼠补铁,并与甘氨酸螯合铁和硫酸亚铁进行比较。结果表明,甘氨酸螯合铁纳米脂质体能够显著增加大鼠血液中血红蛋白含量,提高血清铁含量,降低血清总铁结合力(P
| 英文摘要:
| The effect of ferrous glycinate nanoliposomes on iron-deficiency anemia was investigated through comparing with that of ferrous glycinate and ferrous sulfate on SD rats..Hb,serum Fe,total iron binding capacity,iron contents of liver and spleen were determined at the end of the intervention,and significant effects were observed for Hb,serum Fe,total iron binding capacity,and iron contents of liver and spleen(P
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