鱼腥草黄酮对小鼠的抗疲劳作用

Anti-Fatigue Activity of Flavonoids from Herbahouttuynia

DOI：10.3969/j.issn.1673-1689.2012.02.013

中文关键词: 鱼腥草黄酮 抗疲劳 小鼠

英文关键词: flavonoids from herbahouttuynia anti-fatigue mice

基金项目:湖北省自然科学基金项目(2008C2021102)

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中文摘要:

探讨鱼腥草黄酮对体力疲劳的缓解作用。将128只小鼠随机分对照组,鱼腥草黄酮低、中、高剂量治疗组(40,80、160mg/kg);采用灌胃法,对照组给予等量蒸馏水,连续28d。小鼠体重,负重游泳时间,血乳酸、血清尿素氮和肝(肌)糖原的浓度等指标被测定。结果显示鱼腥草黄酮显著延长小鼠负重游泳时间,清除血乳酸堆积或抑制血乳酸的产生,减缓机体运动后含氮物质的分解,增加运动小鼠肝(肌)糖原的储备,具有显著的抗疲劳活性。

英文摘要:

The objective of this study is to investigate the anti-fatigue activity of flavonoids from herbahouttuynia(FFH).For this,128 male mice were divided into control group,low-dose FFH treated group,medium-dose FFH treated group and high-dose FFH treated group.The control group was given dH2O and the treatment groups were given FFH(40,80、160 mg/kg) for 28 days.Body weight,blood lactic acid(BLA),serum blood urea nitrogen(BUN),tissue glycogen(liver and glycogen) concentrations in mice were determined.The results demonstrated that FFH extended the exhaustive exercise time of mice,effectively delayed the increasing of blood lactic acid,increasing the storage of tissue glycogen.From the above results,it can draw the conclusion that FFH exhibited significant anti-fatigue activity

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