| 牛磺酸对大鼠铁利用和抗氧化能力的影响
| Effects of Taurine on Iron Utilization and Antioxidative Ability of Rats
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| DOI：10.3969/j.issn.1673-1689.2013.05.016
| 中文关键词: 牛磺酸 大鼠 缺铁性贫血 铁利用 抗氧化
| 英文关键词: taurine rat iron deficiency anemia iron utilization antioxidant
| 基金项目:浙江省省级公益性技术应用研究计划项目(2011C22026);浙江省博士后科研择优资助项目;舟山市普陀区科学技术局2012年科技项目
| 作者
| 单位
| 王芙蓉
| 舟山普陀海洋高科技园区,浙江舟山316100
浙江大学生物工程与食品学院,浙江杭州310029
| 谢中国
| 舟山普陀海洋高科技园区,浙江舟山,316100
| 叶兴乾
| 浙江大学生物工程与食品学院,浙江杭州,310029
| 邓尚贵
| 浙江海洋学院食品与药学学院、医学院,浙江舟山,316000
| 陈士国
| 浙江大学生物工程与食品学院,浙江杭州,310029
| 胡亚芹
| 浙江大学生物工程与食品学院,浙江杭州,310029
| 肖定福
| 湖南农业大学动物科学技术学院,湖南长沙,410128
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| 中文摘要:
| 研究了牛磺酸对缺铁性贫血大鼠和正常大鼠铁利用和抗氧化能力的影响。通过对SD大鼠喂养缺铁饲料,建立缺铁性贫血大鼠模型,再给缺铁性贫血大鼠和正常大鼠灌胃0.5 g/kg牛磺酸共21 d,比较牛磺酸对正常大鼠和缺铁性贫血大鼠铁利用和抗氧化能力的影响。结果表明,牛磺酸可显著提高缺铁性贫血大鼠血红蛋白含量,提高血清铁和铁蛋白含量,提高肝脏铁含量,降低血清总铁结合力(P0.05)。因此,牛磺酸对缺铁性贫血大鼠铁的利用和抗氧化能力的提高效果优于正常大鼠。
| 英文摘要:
| The aim of this manuscript was to investigate the effects of taurine on iron utilization and antioxidative ability of iron deficiency anemia(IDA) rats and normal rats,for those,the iron utilization and antioxidative ability in IDA rats and normal rats were determined after gavaged 0.5 g/kg taurine for 21 days.The IDA rat model was established through fed iron deficiency feed to the SD rats Hemoglobin,serum iron,serum ferritin,total iron binding capacity and the content of liver and spleen iron,MDA,SOD,GSH-Px and T-AOC were determined respectively after the end of the intervention.It was found that the addition of taurine in IDA rats increased hemoglobin,serum iron,serum ferritin,the content of liver iron and decreased the total iron binding capacity significantly(P0.05).Therefore,the effects of taurine on iron utilization and antioxidative ability in the IDA rats were better than that of the normal rats.
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