基于RSCU与QRSCU的F/10和G/11木聚糖酶家族密码子偏好性的比较

Based on RSCU and QRSCU Research Codon Bias of F/10 and G/11 Xylanase

DOI：

中文关键词: 木聚糖酶 拟氨基酸基因编码 密码子偏好性 RSCU QRSCU

英文关键词: xylanase quasi-amino acids codon bias RSCU QRSCU

基金项目:财政部专项资金项目(200709017);江南大学创新团队发展计划项目

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中文摘要:

分别计算了F/10和G/11木聚糖酶家族的同义密码子的相对使用度和拟相对使用度,即RSCU和QRSCU.通过分析和比较得到,基于拟氨基酸基因编码方法能更明显的展示出密码子家族中对同义密码子的一致偏好性.也就是说,基于拟氨基酸基因编码方法下的F/10与G/11木聚糖酶家族更偏好使用密码子-反密码子结合作用强的密码子,恰好是以g/c结尾的密码子,与前人的偏好性研究结果一致,而且进一步验证了拟氨基酸基因编码方法与密码子偏好性的研究结果密切相关.

英文摘要:

According to the work of Shi Xiufan et al.(2000 Chinese Science Bulletin 45 2520) and Zhu Ping et al.(Chinese physics B,1(2009)),this study computes the relative usage degree of the synonymous codon of F/10 and G/11 Xylanase:(RSCU and QRSCU).Through the analysis and comparison,it was found that the quasi-amino acid shown more consistent preference to the synonymous codon.This result indicated that F/10 and G/11 Xylanase prefer to use the codons with strong combination of the codon-anticodon,just the codons ending with g/c based on the classification of quasi-amino acids.The results present here demonstrated a good accordance with the results that achieved on the 78 human genes and further verified codon preference closely related to quasi-amino acids coding method.

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