乳酸菌食品级表达系统的研究进展

Research Development of LAB Food-Grade Expression System

DOI：10.3969/j.issn.1673-1689.2012.12.001

中文关键词: 乳酸菌 食品级 表达系统 应用

英文关键词: lactic acid bacteria food-grade expression system application

基金项目:农业部现代农业产业技术体系建设专项资金项目(Nycytx-43-kxj4)

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中文摘要:

乳酸菌是一类广泛使用的工业菌。近几十年来,乳酸菌作为同源和异源蛋白表达的宿主菌的潜在应用已得到深入研究,在此基础上建立和发展了乳酸菌食品级基因表达系统。首先介绍了乳酸菌食品级表达系统的一些基本条件,表达和标记系统的适用原则,然后追踪其前沿应用进展情况,对乳酸菌食品级基因表达系统的最新应用进行了归纳,根据此表达系统在当前食品经济中的位置,对其在食品工业、医药和保健品等领域的应用前景进行了展望。

英文摘要:

Lactic acid bacteria(LAB) has been widely used in food industry for centuries.In recent decades,the LAB food-grade expression systems have been established and developed since the potential use of these bacteria as homologous and heterlogous protein expression hosts has been investigated extensively.Here we briefly introduced the basic conditions and principles of the LAB food-grade expression systems,we also summarized and tracked its lastest application development.According to the location of the LAB food-grade expression systems in the food economy,We prospect its application foreground in the areas as follows:food industry,medicine and health protection.

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