富硒大麦苗对小鼠酒精性胃溃疡的防治作用
Protective Effect of Selenium-Enriched Barley Seedling on Ethanol-Induced Gastric Ulcer in Mice
DOI:10.3969/j.issn.1673-1689.2015.12.014
中文关键词: 富硒大麦苗 胃溃疡 溃疡面积比 小鼠
英文关键词: selenium-enriched barley seedling,gastric ulcer,ulcer area ratio,mice
基金项目:
作者
单位
解卫海
鲁东大学 生命科学学院,山东 烟台 264025
王晓洁
肖颜颜
蒋绍霞
烟台正海生物技术有限公司,山东 烟台264006
于镯
侯兰梅
李楠
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中文摘要:
通过建立小鼠酒精性胃溃疡模型,考察了富硒大麦苗对酒精性胃溃疡的影响。分别给小鼠灌服不同剂量的富硒大麦苗汁(0.1、0.5、1 g/mL),采用图像积分法、称质量法、记分法和分级法测量胃壁溃疡的面积与胃总面积的比值(简称溃疡面积比),并对此比值进行统计分析。数据表明,与模型组比较,富硒大麦苗组能有效预防小鼠酒精性胃溃疡的发生(P
英文摘要:
The present work aimed to investigate the influence of selenium-enriched barley seedling on ethanol-induced gastric ulcer by establishing a mice model of ethanol-induced gastric ulceration. The model mice were orally administered SEBS at different doses (0.1,0.5,1 g/mL). The ratio of ulcer area to total stomach area (ulcer area ratio,UAR) was quantified by different methods including image integration method,gravimetric method,score method and grading method. The results were analyzed using statistic analysis. The ethanol-induced gastric ulcer in mice could be effectively prevented by SEBS (P
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